OBJECTIVE To synthesize the presumable bone-targeting nonsteroidal anti-inflammatory agents.METHODS L-Asp6 was prepared by aspartic acid which was protected.

目合具有骨靶向非甾体抗炎药。

PASP-PEG block structure copolymer,comb shaped PASP-PEG block structure copolymer,aspartic acid and glycine,glutamic acid or propalanine copolymer are prepared.

还以对聚天冬侧链进行改,引入烷基或烯烃基、反应活高基酯、磺基等功基团,使其得到更广泛应用。

Aspartic acid An AMINO ACID formed by transamination, in which the amino group of dlutamic acid is transferred to oxaloacetic acid.

由转基作用形一种基，谷基基团被转移到草酰乙中。

The tripeptide Arginyl-Glycyl-Aspartic acid (RGD) is a common cell recognition site of many adhesive proteins contained in extracellular matrices and in the blood .

RGD三肽（精酰-甘酰-天冬）序列是细胞外基质及血液中许多粘附蛋白共有细胞识别位点。